Methyl 3'-nitro[1,1'-biphenyl]-4-carboxylate → Methyl 4-(3-aminophenyl)benzoate
반응식
[N+:1]([C:4]1[CH:5]=[C:6]([C:10]2[CH:15]=[CH:14][C:13]([C:16]([O:18][CH3:19])=[O:17])=[CH:12][CH:11]=2)[CH:7]=[CH:8][CH:9]=1)([O-])=O>O1CCCC1.[Pd]>[NH2:1][C:4]1[CH:5]=[C:6]([C:10]2[CH:15]=[CH:14][C:13]([C:16]([O:18][CH3:19])=[O:17])=[CH:12][CH:11]=2)[CH:7]=[CH:8][CH:9]=1참가 물질
4
실험 절차
In 100 ml of tetrahydrofuran was dissolved 2.70 g of methyl 3'-nitro-biphenyl-4-carboxylate obtained in Reference Example 8. To the solution was added 1.0 g of 10% palladium-on-carbon and the mixture was subjected to catalytic reduction for 2 hours. After removing the catalyst by filtration, the solvent was removed under reduced pressure to obtain 2.34 g of the titled compound.
후처리
- customobtained in Reference Example 8
- customAfter removing the catalyst
- filtrationby filtration
- customthe solvent was removed under reduced pressure
출처 및 근거
- ORD 기록
- ord-da207b51dff04d0497f68fd1ffe0089e
- 출처 데이터셋
- uspto-grants-1997_02
- 특허 번호
- US05599813
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