Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Formaldehyde → 9-(4'-(2"-Hydroxy1"-oxoethyl)-benzylidene)-8-ketotricyclo[5.2.1.02.6]decane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Formaldehyde | HCID 712 | — |
| 반응물 | 4,7-Methano-5H-inden-5-one, octahydro- | HCID 96509 | — |
| 반응물 | 3-Ethyl-1,3-benzothiazol-3-ium bromide | HCID 182081 | — |
| 반응물 | Sodium Methoxide | HCID 10942334 | — |
| 반응물 | 9-(4-Formylbenzylidene)-8-ketotricyclo[5.2.1.02,6]decane | HCID 54022151 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Triethylamine | HCID 8471 | — |
| 생성물 | 9-(4'-(2"-Hydroxy1"-oxoethyl)-benzylidene)-8-ketotricyclo[5.2.1.02.6]decane | HCID 56973744 | — |
반응 단계
0.8 g (3.5 mmol) of 3-ethylbenzothiazolium bromide and triethylamine are added to a mixture of 35 mmol of 9-(4'- formylbenzylidene)-8-ketotricyclo[5.2.1.02.6 ]decane (prepared from 8-ketotricyclo[5.2.1.02.6 ]decane and terephthaldehyde di ethyl acetal (sic) in the presence of sodium methylate and subsequent acetal cleavage) and 1.2 g of paraformaldehyde in 70 ml of ethanol, and the mixture is heated under reflux. After working up analogously to Example 1, 9-(4'-(2"-hydroxy1"-oxoethyl)-benzylidene)-8-ketotricyclo[5.2.1.02.6 ]decane is obtained. The spectra correspond to the expected compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05600007 |
| 출처 데이터셋 | uspto-grants-1997_02 |
| ORD ID | ord-457efa6a1ee94a7ba76ea7bc0b33d250 |
| 출처 메모 | uspto-grants-1997_02 |