Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sulfuric Acid → 3-Bromo-4-chloro-5-fluoro-2-picoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | Bromine | HCID 24408 | — |
| 반응물 | 4-Chloro-5-fluoro-2-methylpyridine | HCID 19691410 | — |
| 생성물 | 3-Bromo-4-chloro-5-fluoro-2-picoline | HCID 19691436 | — |
반응 단계
4-Chloro-5-fluoro-2-picoline, the product of Example 66, is treated with bromine in fuming sulfuric acid containing 65% sulfur trioxide for 7 hours at 80° C. as described by L. van der Does and H. J. Hertog in Rec Trav Chim 81:864 (1965) to afford the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05599816 |
| 출처 데이터셋 | uspto-grants-1997_02 |
| ORD ID | ord-50b7ea4af53a4eae90f99f37b3400dbd |
| 출처 메모 | uspto-grants-1997_02 |