Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,5-Dichloronitrobenzene → 2-Chlorodibenz(b,f)-1,4-oxazepin-11(10H)-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,5-Dichloronitrobenzene | HCID 6977 | — |
| 반응물 | HCID 86750311 | HCID 86750311 | — |
| 생성물 | 2-Chlorodibenz(b,f)-1,4-oxazepin-11(10H)-one | HCID 76619 | — |
반응 단계
The starting material 8-chloro-10,11-dihydro-dibenz[b,f][1,4]oxazepin-11-one was prepared according to the procedures reported in Coyne et al (J. Med. Chem., 1967, 10:541). Briefly, this entailed coupling potassium salicylaldehyde with 2,5-dichloronitrobenzene, followed by oxidation to carboxylic acid, reduction of nitro, and finally ring closure, to yield the desired 8-chloro starting material.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05602120 |
| 출처 데이터셋 | uspto-grants-1997_02 |
| ORD ID | ord-e19f0043f5184b1b8ea158f02f942967 |
| 출처 메모 | uspto-grants-1997_02 |