Phosphorus pentachloride → Butylsulfamyl chloride

HRID 1450193노트

반응식

HRID 1450193 반응식
[CH2:1]([NH:5][S:6](=[O:9])(=O)[OH:7])[CH2:2][CH2:3][CH3:4].P(Cl)(Cl)(Cl)(Cl)[Cl:11]>C1C=CC=CC=1>[CH2:1]([NH:5][S:6]([Cl:11])(=[O:9])=[O:7])[CH2:2][CH2:3][CH3:4]

참가 물질

4

반응물 2

HCID 24819Phosphorus pentachlorideHCID 3628384butylsulfamic acid

생성물 1

HCID 13544378Butylsulfamyl chloride

시약·촉매·용매 1

HCID 241Benzene용매

실험 절차

A suspension of n-butyl sulfamic acid (1.92 gm, 12.53 mmoles) and phosphorus pentachloride (2.61 gm, 12.53 mmoles) in benzene (20 mL) was warmed gently to initiate gas evolution. The reaction mixture was stirred at room temperature for 0.5 h., during which time a cloudy solution resulted. The cloudy solution was heated to reflux for 0.5 h., then was concentrated. The product n-butyl sulfamoyl chloride was isolated by vacuum distillation (120 C., 300 millitorr), 730 mg (liq.) (34%).

후처리

  1. temperaturewas warmed gently
  2. customresulted
  3. temperatureThe cloudy solution was heated
  4. temperatureto reflux for 0.5 h.
  5. concentrationwas concentrated

출처 및 근거

ORD 기록
ord-91f51cd9b03c421d845e01e93d10e8e2
출처 데이터셋
uspto-grants-1997_02
특허 번호
US05602119

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