2,4-anhydro-3,5-bis-O-(phenylmethyl)-D-lyxonic acid methyl ester → HCID 15725611, 화합물
반응식
[CH3:1][O:2][C:3]([C@H:5]1[O:16][C@H:15]([CH2:17][O:18]CC2C=CC=CC=2)[C@@H:6]1[O:7]CC1C=CC=CC=1)=[O:4].[H][H]>[OH-].[OH-].[Pd+2].CO>[CH3:1][O:2][C:3]([C@H:5]1[O:16][C@H:15]([CH2:17][OH:18])[C@@H:6]1[OH:7])=[O:4]참가 물질
5
실험 절차
A slurry of 1.01 g of 2,4-anhydro-3,5-bis-O-(phenylmethyl)-D-lyxonic acid methyl ester (prepared by the procedure in Tetrahedron Letters, Vol 31, No. 33, p4787, 1990), 0.253 g of palladium hydroxide on carbon, and 30 ml of methyl alcohol is hydrogenated under a balloon of hydrogen (1 atm.) for 2.5 hours. The mixture is filtered through diatomaceous earth, washed with ethyl acetate and ethyl alcohol, and concentrated in vacuo to give 0.460 g of the desired product.
후처리
- filtrationThe mixture is filtered through diatomaceous earth
- washwashed with ethyl acetate and ethyl alcohol
- concentrationconcentrated in vacuo
출처 및 근거
- ORD 기록
- ord-29a33b99a75040c3b4c5868a708ae4db
- 출처 데이터셋
- uspto-grants-1997_02
- 특허 번호
- US05602118
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