HCID 15200703, 화합물 → HCID 19972869, 화합물

HRID 1451701노트

반응식

HRID 1451701 반응식
[CH3:1][N:2]([CH3:27])[C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[CH:22]=[CH:21][NH:20][C:19]3[C:18](=[O:23])[C:17]4[NH:16][C:15](=[O:24])[CH:14]=[C:13]([CH3:25])[C:12]=4[C:11](=[O:26])[C:10]2=3)=[CH:5][CH:4]=1>C1(C)C(C)=CC=CC=1>[CH3:27][N:2]([CH3:1])[C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:22]=[CH:21][N:20]=[C:19]3[C:10]=2[C:11](=[O:26])[C:12]2[C:13]([CH3:25])=[CH:14][C:15](=[O:24])[NH:16][C:17]=2[C:18]3=[O:23])=[CH:5][CH:4]=1

참가 물질

3

반응물 1

HCID 15200703HCID 15200703, 화합물

생성물 1

HCID 19972869HCID 19972869, 화합물수율 80%

시약·촉매·용매 1

HCID 7237O-Xylene용매

실험 절차

A solution of 25 mg (0.07 mmol) of 3 in xylene (60 ml) was refluxed for 16 hours while air was bubbling through the solution. After evaporation of the solvent, the residue was purified by silica gel chromatography, using ethyl acetate as eluent to yield 20 mg (80%) of 6.

후처리

  1. customwas bubbling through the solution
  2. customAfter evaporation of the solvent
  3. customthe residue was purified by silica gel chromatography

출처 및 근거

ORD 기록
ord-91b37fa60f194ae0b03532e900609a18
출처 데이터셋
uspto-grants-1997_02
특허 번호
US05605905

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