Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,5,6,7-Tetrahydro-4H-indol-4-one → 1,5,6,7-Tetrahydro-indol-4-one oxime
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,5,6,7-Tetrahydro-4H-indol-4-one | HCID 280229 | — |
| 반응물 | Hydroxyamine hydrochloride | HCID 443297 | — |
| 반응물 | Sodium Acetate | HCID 517045 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 1,5,6,7-Tetrahydro-indol-4-one oxime | HCID 915677 | — |
반응 단계
A solution of 6.08 g of sodium acetate, 5.15 g of hydroxylamine hydrochloride, and 5.25 g of 4-keto-4,5,6,7-tetrahydro indole in 12 mL of water and 36 mL of ethanol was heated at 50° C. for 3 hr, quenched in water, extracted with ethyl acetate and dried over magnesium sulfate. The solvents were removed in vacuo to give a mixture of oxime isomers which was characterized by NMR and Mass spectroscopy.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05606054 |
| 출처 데이터셋 | uspto-grants-1997_02 |
| ORD ID | ord-67f58450e7b44dd5893acb47d5bfeea7 |
| 출처 메모 | uspto-grants-1997_02 |