Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetone → Benzo[1,3]dioxole-2,2-dicarboxylic acid diethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetone | HCID 180 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Diethyl bromomalonate | HCID 69637 | — |
| 반응물 | 2-Oxazolidinone | HCID 73949 | — |
| 생성물 | Benzo[1,3]dioxole-2,2-dicarboxylic acid diethyl ester | HCID 12969876 | — |
반응 단계
A mixture of 0.240 g of the above oxazolidinone, 0.250 g of diethylbromomalonate, 0.500 g of anhydrous potassium carbonate and 10 ml of acetone is stirred overnight, filtered, washed with acetone and evaporated to a brown oil. The oil is purified by flash chromatography, eluting with 5% acetone/toluene. The pure fractions are combined and evaporated giving (S,R)-5-(1-naphthyloxymethyl)-2-oxo-3-oxazolidinyl)propyl)-1,3-benzodioxole-2,2-dicarboxylic acid, diethyl ester as a colorless oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05606069 |
| 출처 데이터셋 | uspto-grants-1997_02 |
| ORD ID | ord-4e8b0a2bc98544b3b014761d8d87e044 |
| 출처 메모 | uspto-grants-1997_02 |