Bromine → 5-Bromo-3,3-dimethylbenzofuran-2(3H)-one

HRID 1453039

반응식

HRID 1453039 반응식
[CH3:1][C:2]1([CH3:12])[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[O:4][C:3]1=[O:11].[Br:13]Br>C(O)(=O)C>[Br:13][C:8]1[CH:9]=[CH:10][C:5]2[O:4][C:3](=[O:11])[C:2]([CH3:12])([CH3:1])[C:6]=2[CH:7]=1

참가 물질

4

반응물 2

HCID 24408BromineHCID 5956202(3H)-Benzofuranone, 3,3-dimethyl-

생성물 1

HCID 162206345-Bromo-3,3-dimethylbenzofuran-2(3H)-one

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

3,3-Dimethyl-3H-benzofuran-2-one (2.81 g, 17.3 mmol) was added to a solution of Bromine (1.51 mL, 29.5 mmoL) and Acetic acid (35 mL) at room temperature, then stirred overnight. The resulting mixture was stripped of solvent, then distilled under high vacuum. The product fraction (2.08 g, 50%) was collected between 65° C. and 79° C.

후처리

  1. distillationdistilled under high vacuum
  2. customThe product fraction (2.08 g, 50%) was collected between 65° C. and 79° C.

출처 및 근거

ORD 기록
ord-574d6c0f386d429f874c195961ed76fc
출처 데이터셋
uspto-grants-2009_01
특허 번호
US07473790B2

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