Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Ethylpiperidine → 4-(2-Butynyloxy)-6-(2-ethylpiperidino)pyrimidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Ethylpiperidine | HCID 94205 | — |
| 반응물 | 4-(2-Butynyloxy)-6-chloropyrimidine | HCID 12137602 | — |
| 생성물 | 4-(2-Butynyloxy)-6-(2-ethylpiperidino)pyrimidine | HCID 59341136 | 32.9% |
반응 단계
0.3 g of 4-chloro-6-(2-butynyloxy)pyrimidine and 0.56 g of 2-ethylpiperidine were mixed and left for 18 hours at 80° C. The reaction mixture was cooled to near room temperature and subjected to silica gel column chromatography to obtain 0.14 g of 4-(2-butynyloxy)-6-(2-ethylpiperidino)pyrimidine (hereinafter, referred to as Compound (22)).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07732448B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-04ef764e85d64f98abad7fe047736f5c |
| 출처 메모 | uspto-grants-2010_06 |