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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1453514생성일: 2026년 10월 26일

p-Toluic acid, 2,3,5,6-tetrafluoro- → (S)-2,3,5,6-tetrafluoro-4-methyl-N-(3-methylbutan-2-yl)benzamide

https://huagongshe.com/reaction/1453514

반응식

참여 물질

역할이름HCID투입량
반응물p-Toluic acid, 2,3,5,6-tetrafluoro-HCID 69548—
반응물1,2-Dimethylpropylamine, (S)-HCID 6999788—
생성물(S)-2,3,5,6-tetrafluoro-4-methyl-N-(3-methylbutan-2-yl)benzamideHCID 57527834—

반응 단계

Prepared in a similar manner to Example 162 using (S)-3-methylbutan-2-amine and 2,3,5,6-tetrafluoro-p-toluic acid acid (93%). 1H NMR (CDCl3) δ 0.98 (d, J=6.9 Hz, 6H) 1.18 (d, J=6.8 Hz, 3H), 2.29 (m, 3H), 4.09 (m, 1H), 5.72 (bs, 1H). MS (304.1, M+H) m.p. 146-147° C.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07476399B2
출처 데이터셋uspto-grants-2009_01
ORD IDord-3f23872517b148f29260989786929162
출처 메모uspto-grants-2009_01