1-(3-Bromophenyl)-2-(methylamino)ethan-1-ol → HCID 178499182, 화합물

HRID 1453887노트

반응식

HRID 1453887 반응식
[CH2:1]([O:8][C:9]1[C:10]([C:18]([OH:20])=O)=[N:11][NH:12][C:13]=1[C:14]([O:16][CH3:17])=[O:15])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Br:21][C:22]1[CH:23]=[C:24]([CH:28]([OH:32])[CH2:29][NH:30][CH3:31])[CH:25]=[CH:26][CH:27]=1>>[CH2:1]([O:8][C:9]1[C:13]([C:14]([O:16][CH3:17])=[O:15])=[N:12][NH:11][C:10]=1[C:18]([N:30]([CH2:29][CH:28]([C:24]1[CH:25]=[CH:26][CH:27]=[C:22]([Br:21])[CH:23]=1)[OH:32])[CH3:31])=[O:20])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

3

반응물 2

HCID 219434511-(3-Bromophenyl)-2-(methylamino)ethan-1-olHCID 57528495Methyl 4-benzyloxy-3-carboxy-1H-pyrazole-5-carboxylate

생성물 1

HCID 178499182HCID 178499182, 화합물

실험 절차

The title compound was prepared from methyl 4-benzyloxy-3-carboxy-1H-pyrazole-5-carboxylate (prepared as in Example 31, Step 1) using a procedure similar to that described in Example 31, Step 2, except that 1-(3-bromophenyl)-2-(methylamino)ethanol (prepared as described in Tsushima, S., et al., EP 278621 and Cudahy, M. M., et al., WO 2003059911) was used in place of (1R)-2-(methylamino)-1-phenylethanol. ES MS (M+2)=490.

출처 및 근거

ORD 기록
ord-6a1ae8634c3341b5ac75078a74c2853c
출처 데이터셋
uspto-grants-2009_01
특허 번호
US07476666B2

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