Ethylamine → 29526-66-7

HRID 1454271노트

반응식

HRID 1454271 반응식
[CH3:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][C:3]=1[N+:11]([O-])=O.[CH2:14]([NH2:16])[CH3:15]>C(Cl)Cl>[NH2:11][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][C:2]=1[CH3:1])[C:6]([NH:16][CH2:14][CH3:15])=[O:7]

참가 물질

4

반응물 2

HCID 6341EthylamineHCID 663234-Methyl-3-nitrobenzoyl chloride

생성물 1

HCID 1260797429526-66-7

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

4-methyl-3-nitro-benzoyl chloride (1.0 g, 5.0 mmol) was dissolved in DCM, and the solution was cooled to 0EC. Ethyl amine (2.0M in THF, 5.0 mL, 10 mmol) was added dropwise to the acid chloride, and the reaction stirred at 0EC for 5 min. The ice bath was removed and reaction continued to stir for 3. The solution was washed with brine, dried (Na2SO4), and concentrated in vacuo. The resulting aniline (0.75 g) was used without further purification.

후처리

  1. temperaturethe solution was cooled to 0EC
  2. customThe ice bath was removed
  3. customreaction
  4. stirringto stir for 3
  5. washThe solution was washed with brine
  6. dry with materialdried (Na2SO4)
  7. concentrationconcentrated in vacuo
  8. customThe resulting aniline (0.75 g) was used without further purification

출처 및 근거

ORD 기록
ord-d5e2d6173e7144c698fdce63bee20613
출처 데이터셋
uspto-grants-2009_01
특허 번호
US07479495B2

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