Ethyl-5-bromo-2-carboxypyridine → 1-(5-Bromopyridin-2-yl)cyclopentan-1-ol
반응식
C([C:3]1[C:4]([C:10]([OH:12])=O)=[N:5][CH:6]=[C:7]([Br:9])[CH:8]=1)C>C(OCC)C>[Br:9][C:7]1[CH:8]=[CH:3][C:4]([C:10]2([OH:12])[CH2:7][CH2:8][CH2:3][CH2:4]2)=[N:5][CH:6]=1참가 물질
3
실험 절차
The title compound was prepared using ethyl-5-bromo-2-carboxypyridine, 1,4-bis (bromomagnesium) butane and diethyl ether as solvent, but otherwise followed the general procedure for Preparation 36. 13C NMR (100 MHz, CDCl3) d 164.1, 148.9, 139.5, 120.9, 118.8, 83.2, 42.7, 24.9; MS (AP/Cl) 242.1, 244.1 (M+H)+.
후처리
- customfor Preparation 36
출처 및 근거
- ORD 기록
- ord-11c64e62e8c84a3e82c21855e36b08a1
- 출처 데이터셋
- uspto-grants-2009_01
- 특허 번호
- US07479559B2
반응 노트
불러오는 중…