4-Aminophenethyl alcohol → 6-[4-(2-Hydroxyethyl)anilino]-2,4-dimethyl-5-nitronicotinonitrile

HRID 1454613노트

반응식

HRID 1454613 반응식
Cl[C:2]1[C:9]([N+:10]([O-:12])=[O:11])=[C:8]([CH3:13])[C:5]([C:6]#[N:7])=[C:4]([CH3:14])[N:3]=1.[NH2:15][C:16]1[CH:21]=[CH:20][C:19]([CH2:22][CH2:23][OH:24])=[CH:18][CH:17]=1>>[OH:24][CH2:23][CH2:22][C:19]1[CH:20]=[CH:21][C:16]([NH:15][C:2]2[C:9]([N+:10]([O-:12])=[O:11])=[C:8]([CH3:13])[C:5]([C:6]#[N:7])=[C:4]([CH3:14])[N:3]=2)=[CH:17][CH:18]=1

참가 물질

3

반응물 2

HCID 669044-Aminophenethyl alcoholHCID 218761896-Chloro-2,4-dimethyl-5-nitronicotinonitrile

생성물 1

HCID 218758146-[4-(2-Hydroxyethyl)anilino]-2,4-dimethyl-5-nitronicotinonitrile

실험 절차

The title compound was prepared according to the procedure described in step 3 of Example 1 from 6-chloro-2,4-dimethyl-5-nitronicotinonitrile (step 3) and 4-aminophenylethyl alcohol.

출처 및 근거

ORD 기록
ord-6787d04c89474ec088b41eee9ce3420a
출처 데이터셋
uspto-grants-2009_01
특허 번호
US07479564B2

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