2,4-Dichloro-5-nitrobenzotrifluoride → (2r)-1-(4-{[5-Chloro-2-nitro-4-(trifluoromethyl)phenyl]amino}phenyl)-2-propanol

HRID 1454686노트

반응식

HRID 1454686 반응식
[Cl:1][C:2]1[CH:7]=[C:6](Cl)[C:5]([N+:9]([O-:11])=[O:10])=[CH:4][C:3]=1[C:12]([F:15])([F:14])[F:13].[NH2:16][C:17]1[CH:22]=[CH:21][C:20]([CH2:23][C@H:24]([OH:26])[CH3:25])=[CH:19][CH:18]=1>>[Cl:1][C:2]1[C:3]([C:12]([F:15])([F:14])[F:13])=[CH:4][C:5]([N+:9]([O-:11])=[O:10])=[C:6]([NH:16][C:17]2[CH:18]=[CH:19][C:20]([CH2:23][C@H:24]([OH:26])[CH3:25])=[CH:21][CH:22]=2)[CH:7]=1

참가 물질

3

반응물 2

HCID 6211792,4-Dichloro-5-nitrobenzotrifluorideHCID 67099545(2R)-1-(4-aminophenyl)-2-propanol

생성물 1

HCID 67099586(2r)-1-(4-{[5-Chloro-2-nitro-4-(trifluoromethyl)phenyl]amino}phenyl)-2-propanol

실험 절차

The title compound was prepared according to the procedure described in step 1 of Example 162 from 2,4-dichloro-5-nitrobenzotrifluoride and (2R)-1-(4-aminophenyl)-2-propanol (step 2 of Example 249).

출처 및 근거

ORD 기록
ord-b9c213b3a6f74e39b16e4e486ce82435
출처 데이터셋
uspto-grants-2009_01
특허 번호
US07479564B2

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