HCID 68526884, 화합물 → HCID 68864310, 화합물

HRID 1454768노트

반응식

HRID 1454768 반응식
[C:1]([C:4]12[CH2:13][CH:8]([C:9]([CH3:12])=[CH:10][CH2:11]1)[C:7](=[O:14])[CH2:6][CH:5]2[CH3:15])([CH3:3])=[CH2:2]>CO.[Pd]>[CH:1]([C:4]12[CH2:13][CH:8]([CH:9]([CH3:12])[CH2:10][CH2:11]1)[C:7](=[O:14])[CH2:6][CH:5]2[CH3:15])([CH3:3])[CH3:2]

참가 물질

4

반응물 1

HCID 68526884HCID 68526884, 화합물

생성물 1

HCID 68864310HCID 68864310, 화합물수율 22%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

At 25° C., a mixture of 1 g 5-isopropenyl-4,8-dimethylbicyclo[3.3.1]non-7-en-2-one (4.9 mmol) and 50 mg 10% Pd/C in 10 ml MeOH was stirred under 10 bar of H2 for 5 h. Filtration (Celite®), concentration, and FC (SiO2, hexane/Et2O 100:7) gave 0.22 g (22%) of compound 9. The boiling point of the end product is 75° C. at 0.07 torr (0.09 mbar).

후처리

  1. filtrationFiltration (Celite®), concentration, and FC (SiO2, hexane/Et2O 100:7)

출처 및 근거

ORD 기록
ord-ef4b92b6eea3482b8b962f85aafe2ed1
출처 데이터셋
uspto-grants-2009_01
특허 번호
US07482313B2

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