2,5-Difluorobenzenesulfonyl chloride → HCID 11619172, 화합물

HRID 1454831노트

반응식

HRID 1454831 반응식
[F:1][C:2]([F:19])([F:18])[C:3]1[CH:17]=[CH:16][C:6]([O:7][CH2:8][C:9]2[N:14]=[C:13]([NH2:15])[CH:12]=[CH:11][CH:10]=2)=[CH:5][CH:4]=1.[F:20][C:21]1[CH:26]=[CH:25][C:24]([F:27])=[CH:23][C:22]=1[S:28](Cl)(=[O:30])=[O:29]>>[F:20][C:21]1[CH:26]=[CH:25][C:24]([F:27])=[CH:23][C:22]=1[S:28]([NH:15][C:13]1[CH:12]=[CH:11][CH:10]=[C:9]([CH2:8][O:7][C:6]2[CH:16]=[CH:17][C:3]([C:2]([F:1])([F:18])[F:19])=[CH:4][CH:5]=2)[N:14]=1)(=[O:30])=[O:29]

참가 물질

3

반응물 2

HCID 27369112,5-Difluorobenzenesulfonyl chlorideHCID 68842874HCID 68842874, 화합물

생성물 1

HCID 11619172HCID 11619172, 화합물

실험 절차

This material was prepared in analogy to example 1 from 6-(4-trifluoromethyl-phenoxymethyl)-pyridin-2-ylamine (0.08 g) and 2,5-difluoro-benzenesulfonyl chloride (0.07 g) as a light yellow solid (0.086 g). MS (ESI−): 443.0 ([M−H]−)

출처 및 근거

ORD 기록
ord-e92040a0dbbf4025bf51f041dc43c441
출처 데이터셋
uspto-grants-2009_01
특허 번호
US07482341B2

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