2,4-Dichloro-5-methylbenzene-1-sulphonyl chloride → 2,4-Dichloro-5-methyl-N-[6-(2,2,2-trifluoro-ethoxymethyl)-pyridin-2-yl]-benzenesulfonamide

HRID 1454899

반응식

HRID 1454899 반응식
[F:1][C:2]([F:14])([F:13])[CH2:3][O:4][CH2:5][C:6]1[N:11]=[C:10]([NH2:12])[CH:9]=[CH:8][CH:7]=1.[Cl:15][C:16]1[CH:21]=[C:20]([Cl:22])[C:19]([CH3:23])=[CH:18][C:17]=1[S:24](Cl)(=[O:26])=[O:25]>>[Cl:15][C:16]1[CH:21]=[C:20]([Cl:22])[C:19]([CH3:23])=[CH:18][C:17]=1[S:24]([NH:12][C:10]1[CH:9]=[CH:8][CH:7]=[C:6]([CH2:5][O:4][CH2:3][C:2]([F:1])([F:13])[F:14])[N:11]=1)(=[O:26])=[O:25]

참가 물질

3

반응물 2

HCID 1199142,4-Dichloro-5-methylbenzene-1-sulphonyl chlorideHCID 688453756-(2,2,2-Trifluoro-ethoxymethyl)-pyridin-2-ylamine

생성물 1

HCID 688463842,4-Dichloro-5-methyl-N-[6-(2,2,2-trifluoro-ethoxymethyl)-pyridin-2-yl]-benzenesulfonamide

실험 절차

This material was prepared in analogy to example 1 from 6-(2,2,2-Trifluoro-ethoxymethyl)-pyridin-2-ylamine (0.08 g) and 2,4-dichloro-5-methyl-benzenesulfonyl chloride (0.11 g) as a light yellow gum (0.095 g). MS (ESI−): 427.1 ([M−H]−).

출처 및 근거

ORD 기록
ord-5c18f8527f314738bafa3eba296252a7
출처 데이터셋
uspto-grants-2009_01
특허 번호
US07482341B2

연결된 노트

불러오는 중…