3-(Trifluoromethyl)benzenesulfonyl chloride → HCID 86604243, 화합물

반응식

[F:1][C:2]([F:14])([F:13])[CH2:3][O:4][CH2:5][C:6]1[CH:7]=[CH:8][C:9]([NH2:12])=[N:10][CH:11]=1.[F:15][C:16]([F:28])([F:27])[C:17]1[CH:18]=[C:19]([S:23](Cl)(=[O:25])=[O:24])[CH:20]=[CH:21][CH:22]=1>>[F:14][C:2]([F:1])([F:13])[CH2:3][O:4][CH2:5][C:6]1[CH:7]=[CH:8][C:9]([NH:12][S:23]([C:19]2[CH:20]=[CH:21][CH:22]=[C:17]([C:16]([F:15])([F:27])[F:28])[CH:18]=2)(=[O:25])=[O:24])=[N:10][CH:11]=1

참가 물질

반응물 2

HCID 27332503-(Trifluoromethyl)benzenesulfonyl chloride

HCID 62193320HCID 62193320, 화합물

생성물 1

HCID 86604243HCID 86604243, 화합물

실험 절차

This material was prepared in analogy to example 1 from 5-(2,2,2-Trifluoro-ethoxymethyl)-pyridin-2-ylamine (0.06 g) and 3-(trifluoromethyl)-benzenesulfonyl chloride (0.078 g) as an off-white solid (0.056 g). MS (ESI−): 413.1 ([M−H]−).

출처 및 근거

ORD 기록: ord-0a1c850704284816b2fdd16cba03d384
출처 데이터셋: uspto-grants-2009_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07482341B2

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