1,3-Dibromobenzene → 4-(3-Bromophenyl)pyridine

HRID 1455649노트

반응식

HRID 1455649 반응식
[N:1]1[CH:6]=[CH:5][C:4](B(O)O)=[CH:3][CH:2]=1.[Br:10][C:11]1[CH:16]=[CH:15][CH:14]=[C:13](Br)[CH:12]=1.CCCCCC>CCOC(C)=O>[Br:10][C:11]1[CH:12]=[C:13]([C:4]2[CH:5]=[CH:6][N:1]=[CH:2][CH:3]=2)[CH:14]=[CH:15][CH:16]=1

참가 물질

5

반응물 3

HCID 79271,3-DibromobenzeneHCID 8058HexaneHCID 2734379(Pyridin-4-yl)boronic acid

생성물 1

HCID 131504024-(3-Bromophenyl)pyridine

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

실험 절차

Prepared according to the general procedure Coupling-1 using 4-pyridinylboronic acid and 1,3-dibromobenzene. Flash chromatography (Hexane:EtOAc, 70:30) afforded the title compound.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-11777189074d4987b67e942c04f208c1
출처 데이터셋
uspto-grants-2009_01
특허 번호
US07482456B2

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