Valproate → Magnesium Valproate

HRID 1455714

반응식

HRID 1455714 반응식
[C:1]([O-:10])(=[O:9])[CH:2]([CH2:6][CH2:7][CH3:8])[CH2:3][CH2:4][CH3:5].O.[C:12]([O-:21])(=[O:20])[CH:13]([CH2:17][CH2:18][CH3:19])[CH2:14][CH2:15][CH3:16].[Mg+2:22].C([O-])(=O)C(CCC)CCC>O>[C:1]([O-:10])(=[O:9])[CH:2]([CH2:6][CH2:7][CH3:8])[CH2:3][CH2:4][CH3:5].[Mg+2:22].[C:12]([O-:21])(=[O:20])[CH:13]([CH2:17][CH2:18][CH3:19])[CH2:14][CH2:15][CH3:16]

참가 물질

4

반응물 2

HCID 3549980ValproateHCID 71439018Magnesium;bis(2-propylpentanoate);hydrate

생성물 1

HCID 147515Magnesium Valproate

시약·촉매·용매 1

HCID 962Water용매

실험 절차

Surprisingly, the inventors have discovered that a heretofore unknown valproate salt, magnesium valproate hydrate, a white solid having the molecular formula C16H30O4Mg.x H2O, is recovered in high yields from an alcoholic solution of magnesium valproate by adding a polar, non-oxygen-containing organic solvent having a boiling point of about 130° C. or lower in a volume sufficient to reduce the solubility of the magnesium valproate in the resulting reaction mixture to less than about 0.01 g/mL. The polar, non-oxygen-containing organic solvent is acetonitrile, propionitrile, butyronitrile, or isobutyronitrile. Acetonitrile is most preferred.

후처리

  1. customis recovered

출처 및 근거

ORD 기록
ord-6aaabd3d5f824156baa1b3cd9b66066c
출처 데이터셋
uspto-grants-2009_01
특허 번호
US07482486B2

연결된 노트

불러오는 중…