3(S)-(2-((2(S)-Benzoylamino-3-methylbutyryl)benzylamino)acetylamino)-4-(4-(2,6-dichlorophenyl)-oxazol-2-yl)-4-oxobutyric Acid → 3(S)-(2-((2(S)-Benzoylamino-3-methylbutyryl)indan-2-ylamino)acetylamino)-4-(4,6-dichlorobenzoxazol-2-yl)-4-oxobutyric Acid

반응식

[C:1]([NH:9][C@@H:10]([CH:45]([CH3:47])[CH3:46])[C:11]([N:13]([CH2:38][C:39]1C=[CH:43][CH:42]=[CH:41][CH:40]=1)[CH2:14][C:15]([NH:17][C@H](C(C1OC=C(C2C(Cl)=CC=CC=2Cl)N=1)=O)CC(O)=O)=[O:16])=[O:12])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:48](N[C@@H](C(C)C)C(N(CC(O)=O)CC1C=CC=CC=1)=O)(=O)[C:49]1C=CC=C[CH:50]=1.C(OC(=O)C(N)[C@H](C(OCC=C)=O)C(C1OC=C(C2C(Cl)=CC=CC=2Cl)N=1)O)(C)(C)C.C([O:110][C:111](=[O:134])[CH:112](N)[C@H:113](C(OCC=C)=O)[CH:114]([C:116]1[O:117][C:118]2[CH:124]=[C:123]([Cl:125])[CH:122]=[C:121]([Cl:126])[C:119]=2[N:120]=1)[OH:115])(C)(C)C.C(OC(=O)C[C@H](NC(=O)CN(C(=O)[C@@H](NC(=O)C1C=CC=CC=1)C(C)C)CC1C=CC=CC=1)C(C1OC=C(C2C(Cl)=CC=CC=2Cl)N=1)O)(C)(C)C>>[C:1]([NH:9][C@@H:10]([CH:45]([CH3:46])[CH3:47])[C:11]([N:13]([CH:38]1[CH2:50][C:49]2[C:40](=[CH:41][CH:42]=[CH:43][CH:48]=2)[CH2:39]1)[CH2:14][C:15]([NH:17][C@H:113]([C:114]([C:116]1[O:117][C:118]2[CH:124]=[C:123]([Cl:125])[CH:122]=[C:121]([Cl:126])[C:119]=2[N:120]=1)=[O:115])[CH2:112][C:111]([OH:110])=[O:134])=[O:16])=[O:12])(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1