5-Bromoindole → 5-Bromo-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

HRID 1456987노트

반응식

HRID 1456987 반응식
[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[CH:5]2.Cl.O.[NH:13]1[CH2:18][CH2:17][C:16](=O)[CH2:15][CH2:14]1>>[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[C:16]1[CH2:17][CH2:18][NH:13][CH2:14][CH:15]=1

참가 물질

3

반응물 2

HCID 249055-BromoindoleHCID 2723901Piperonylamine

생성물 1

HCID 27637245-Bromo-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole수율 93.5%

실험 절차

Beginning with 6.2 gm (31.6 mMol) 5-bromo-1H-indole and 4.7 gm (30.6 mMol) 4-piperidone monohydrate hydrochloride, 7.93 gm (93%) of the title compound were recovered as a solid.

출처 및 근거

ORD 기록
ord-9d133a30107e47d184991b50b0301833
출처 데이터셋
uspto-grants-1998_12
특허 번호
US05846982

반응 노트

불러오는 중…