3-Furoyl chloride → N-(N,N-Dipropyl-1,2,3,4-tetrahydro-2-aminodibenzofur-8-yl)-3-furamide hydrochloride
반응식
[NH2:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]3[CH2:10][CH2:11][CH:12]([N:14]([CH2:18][CH2:19][CH3:20])[CH2:15][CH2:16][CH3:17])[CH2:13][C:7]=3[C:6]=2[CH:21]=1.[O:22]1[CH:26]=[CH:25][C:24]([C:27]([Cl:29])=[O:28])=[CH:23]1>>[ClH:29].[CH2:15]([N:14]([CH2:18][CH2:19][CH3:20])[CH:12]1[CH2:11][CH2:10][C:8]2[O:9][C:5]3[CH:4]=[CH:3][C:2]([NH:1][C:27]([C:24]4[CH:25]=[CH:26][O:22][CH:23]=4)=[O:28])=[CH:21][C:6]=3[C:7]=2[CH2:13]1)[CH2:16][CH3:17]참가 물질
3
실험 절차
Beginning with 0.072 gm (0.20 mMol) 8-amino-1,2,3,4-tetrahydro-2-dipropylaminodibenzofuran and 0.026 gm (0.20 mMol) furan-3-carbonyl chloride, 0.064 gm (84%) of the title compound were recovered as a white foam by the procedure described in Example 17.
출처 및 근거
- ORD 기록
- ord-4b1fdb4d8b3740be887a09c419470892
- 출처 데이터셋
- uspto-grants-1998_12