Aniline → HCID 57060229, 화합물

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CO[C:3](=[O:23])[C@H:4]([OH:22])[C@@H:5]([S:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[NH2:21])[C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[CH:8][CH:7]=1.[NH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[NH2:21][C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=1[S:14][C@@H:5]([C:6]1[CH:7]=[CH:8][C:9]([O:12][CH3:13])=[CH:10][CH:11]=1)[C@@H:4]([OH:22])[C:3]([NH:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)=[O:23]

참가 물질

반응물 2

HCID 6115Aniline

HCID 10131714Methyl (2S,3S)-3-(2-aminophenyl)sulfanyl-2-hydroxy-3-(4-methoxyphenyl)propanoate

생성물 1

HCID 57060229HCID 57060229, 화합물

실험 절차

(2S,3S)-3-(2-Aminophenylthio)-2-hydroxy-3-(4-methoxyphenyl)-propionic acid methyl ester and aniline are treated in the same manner as in Reference Example 5 to give (2S,3S)-3-(2-aminophenylthio)-2-hydroxy-3-(4-methoxyphenyl)-N-phenylpropionamide.

출처 및 근거

ORD 기록: ord-cb6be9c6a5764e89bc2b0ed5d8e24d44
출처 데이터셋: uspto-grants-1998_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05847122

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