Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4,6-Dichloropyrimidine → 4-Chloro-6-(cis-2,6-dimethylpiperidino)pyrimidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4,6-Dichloropyrimidine | HCID 70943 | — |
| 반응물 | rel-(2R,6S)-2,6-Dimethylpiperidine | HCID 641768 | — |
| 생성물 | 4-Chloro-6-(cis-2,6-dimethylpiperidino)pyrimidine | HCID 86607466 | 27.7% |
반응 단계
0.5 g of 4,6-dichloropyrimidine and 0.76 g of cis-2,6-dimethylpiperidine were mixed and stirred for 10 hours at 90%. The reaction mixture was subjected to silica gel column chromatography to obtain 0.21 g of 4-chloro-6-(cis-2,6-dimethylpiperidino)pyrimidine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07732448B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-f5e9b66fe77449749982e038ebebf7e4 |
| 출처 메모 | uspto-grants-2010_06 |