Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Indole-3-Carboxylic Acid → (1-Benzyl-4-piperidyl)methyl indole-3-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Indole-3-Carboxylic Acid | HCID 69867 | — |
| 반응물 | (1-Benzylpiperidin-4-yl)methanol | HCID 736802 | — |
| 생성물 | (1-Benzyl-4-piperidyl)methyl indole-3-carboxylate | HCID 19599412 | 88% |
반응 단계
Indole-3-carboxylic acid was converted to its acid chloride and then reacted with 1-benzyl-4-piperidinemethanol (D7) using the method given in Example 1a. The resulting orange oil was chromatographed on silica gel eluting with chloroform/ethanol (9:1) to afford (1-benzyl-4-piperidyl)methyl indole-3-carboxylate as a yellow oil (88%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05852014 |
| 출처 데이터셋 | uspto-grants-1998_12 |
| ORD ID | ord-f803b1fddf174cc78f067da1fe213c9a |
| 출처 메모 | uspto-grants-1998_12 |