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HRID 1458614생성일: 2026년 10월 27일

1H-Indole-3-carboxylic acid, 2-chloro- → N-[(1-n butyl-4-piperidyl)methyl]2-chloroindole-3-carboxamide

https://huagongshe.com/reaction/1458614

반응식

참여 물질

역할이름HCID투입량
반응물1H-Indole-3-carboxylic acid, 2-chloro-HCID 99521—
반응물4-Aminomethyl-1-N-butylpiperidineHCID 10442133—
반응물N-[(1-n butyl-4-piperidyl)methyl] indole-3-carboxamideHCID 10591304—
생성물N-[(1-n butyl-4-piperidyl)methyl]2-chloroindole-3-carboxamideHCID 22096969—

반응 단계

2-Chloroindole-3-carboxylic acid (L. Marchetti and A Andreani, Ann. Chim. (Rome), 1973, 63, 681) was converted to its acid chloride and reacted with N-(1-n butyl-4-piperidyl)methylamine (D 1) using the procedure of Description 1b to afford N-[(1-n butyl-4-piperidyl)methyl] 2-chloroindole-3-carboxamide.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05852014
출처 데이터셋uspto-grants-1998_12
ORD IDord-f9cda446b9ad40d18ad12f05a1e650df
출처 메모uspto-grants-1998_12