N-cyclohexyl-2-nitro-4-(trifluoromethyl)aniline → 1-N-cyclohexyl-4-(trifluoromethyl)benzene-1,2-diamine
반응식
[CH:1]1([NH:7][C:8]2[CH:13]=[CH:12][C:11]([C:14]([F:17])([F:16])[F:15])=[CH:10][C:9]=2[N+:18]([O-])=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[H][H]>CO.[Pd]>[CH:1]1([NH:7][C:8]2[CH:13]=[CH:12][C:11]([C:14]([F:15])([F:16])[F:17])=[CH:10][C:9]=2[NH2:18])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1참가 물질
5
실험 절차
32 g (0.11 mol) of N-cyclohexyl-2-nitro-4-trifluoromethylaniline dissolved in 250 ml of methanol were hydrogenated under a pressure of about 1 bar of hydrogen in the presence of 1.5 g of palladium/active carbon (10% by weight Pd) at room temperature. The reaction mixture was filtered. Conventional workup of the filtrate gave a 100% yield of the abovementioned compound.
후처리
- filtrationThe reaction mixture was filtered
출처 및 근거
- ORD 기록
- ord-7f381552dee249ecb561eac63adc3169
- 출처 데이터셋
- uspto-grants-1998_12
- 특허 번호
- US05852017
반응 노트
불러오는 중…