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4-Methyl-1,2,3,6-tetrahydropyridine hydrochloride → 1-[5-Methyl-1-(2-pyrimidinyl)-4-pyrazolyl]-3-[4-methyl-1,2,5,6-tetrahydro-1-pyridyl]-1-trans-propene hydrochloride

HRID 1458979
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HRID 1458979 반응식
[ClH:1].[CH3:2][C:3]1[N:7]([C:8]2[N:13]=[CH:12][CH:11]=[CH:10][N:9]=2)[N:6]=[CH:5][C:4]=1[C:14](=O)[CH2:15][CH2:16][N:17]1[CH2:26][CH2:25][C:24]2[C:19](=CC=C[CH:23]=2)[CH2:18]1.Cl.CC1N(C2N=CC=CN=2)N=CC=1/C=C/CN1CCC2C(=CC=CC=2)C1.Cl.CC1CCNCC=1>>[ClH:1].[CH3:2][C:3]1[N:7]([C:8]2[N:13]=[CH:12][CH:11]=[CH:10][N:9]=2)[N:6]=[CH:5][C:4]=1/[CH:14]=[CH:15]/[CH2:16][N:17]1[CH2:26][CH2:25][C:24]([CH3:23])=[CH:19][CH2:18]1
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참가 물질

4

반응물 3

HCID 132411164-Methyl-1,2,3,6-tetrahydropyridine hydrochlorideHCID 220973011-[5-Methyl-1-(2-pyrimidinyl)-4-pyrazolyl]-3-(1,2,3,4-tetrahydroisoquinolin-2-yl)-1-propanone hydrochlorideHCID 220973051-[5-Methyl-1-(2-pyrimidinyl)-4-pyrazolyl]-3-(1,2,3,4-tetrahydroisoquinolin-2-yl)-1-trans-propene hydrochloride

생성물 1

HCID 220973401-[5-Methyl-1-(2-pyrimidinyl)-4-pyrazolyl]-3-[4-methyl-1,2,5,6-tetrahydro-1-pyridyl]-1-trans-propene hydrochloride

실험 절차

The procedures of Example 6 (1) and (2) were repeated but substituting the 1,2,3,4-tetrahydroisoquinoline hydrochloride employed in Example 6 (1) by 4-methyl-1,2,5,6-tetrahydropyridine hydrochloride. After the completion of the post treatment, the title compound was obtained.

출처 및 근거

ORD 기록
ord-25908a6164f443d3a57bfdb6befb475e
출처 데이터셋
uspto-grants-1998_12
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US05852019

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