Methanol → 4-[(3-Chloro-4-fluorophenyl)amino]-6-cyclopentylmethoxy-7-{2-[4-(2-oxo-tetrahydrofuran-4-yl)-piperazin-1-yl]-ethoxy}-quinazoline
반응식
[CH3:42][OH:43].[Cl:7][c:8]1[cH:9][c:10]([NH:15][c:16]2[n:17][cH:18][n:19][c:20]3[cH:21][c:22]([O:33][CH2:34][CH2:35][N:36]4[CH2:37][CH2:38][NH:39][CH2:40][CH2:41]4)[c:23]([O:26][CH2:27][CH:28]4[CH2:29][CH2:30][CH2:31][CH2:32]4)[cH:24][c:25]23)[cH:11][cH:12][c:13]1[F:14].[O:1]1[C:2](=[O:6])[CH:3]=[CH:4][CH2:5]1>>[O:1]1[C:2](=[O:6])[CH2:3][CH:4]([N:39]2[CH2:38][CH2:37][N:36]([CH2:35][CH2:34][O:33][c:22]3[cH:21][c:20]4[n:19][cH:18][n:17][c:16]([NH:15][c:10]5[cH:9][c:8]([Cl:7])[c:13]([F:14])[cH:12][cH:11]5)[c:25]4[cH:24][c:23]3[O:26][CH2:27][CH:28]3[CH2:29][CH2:30][CH2:31][CH2:32]3)[CH2:41][CH2:40]2)[CH2:5]1참가 물질
4
반응물 3
생성물 1
출처 및 근거
- ORD 기록
- ord-efc7b181e6cf447f88a658bca36aac53
- 출처 데이터셋
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
- DOI