(2R,5R)-2,5-dimethylpiperazine → N,N-diethyl-4-(3-hydroxy-alpha-((2R, 5R)-2,5-dimethyl-1-piperazinyl)benzyl)-benzamide

반응식

[CH2:1]([N:3]([CH2:28][CH3:29])[C:4](=[O:27])[C:5]1[CH:10]=[CH:9][C:8]([CH:11](Cl)[C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([O:18][Si](C(C)(C)C)(C)C)[CH:13]=2)=[CH:7][CH:6]=1)[CH3:2].[CH3:30][C@@H:31]1[CH2:36][NH:35][C@H:34]([CH3:37])[CH2:33][NH:32]1.N[C@@H](C(N[C@@H](C(O)=O)C)=O)C.O=C1NCCNC1=O.O.[F-].C([N+](CC)(CC)CC)C>C(#N)C>[CH2:28]([N:3]([CH2:1][CH3:2])[C:4](=[O:27])[C:5]1[CH:10]=[CH:9][C:8]([CH:11]([N:32]2[CH2:33][C@@H:34]([CH3:37])[NH:35][CH2:36][C@H:31]2[CH3:30])[C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([OH:18])[CH:13]=2)=[CH:7][CH:6]=1)[CH3:29]