Water → Ethyl N-allyl-N-(1-oxoprop-2-yl)-carbamate

HRID 1460766

반응식

HRID 1460766 반응식
[CH2:1]([N:4]([CH:10]([CH3:16])[CH:11](OC)[O:12]C)[C:5](=[O:9])[O:6][CH2:7][CH3:8])[CH:2]=[CH2:3].O.[Cl-].[Na+]>C(O)=O>[CH2:1]([N:4]([CH:10]([CH3:16])[CH:11]=[O:12])[C:5](=[O:9])[O:6][CH2:7][CH3:8])[CH:2]=[CH2:3]

참가 물질

5

반응물 3

HCID 962WaterHCID 5234Sodium ChlorideHCID 15069988N-Allyl-N-(1,1-dimethoxyprop-2-yl)-urethane

생성물 1

HCID 15069993Ethyl N-allyl-N-(1-oxoprop-2-yl)-carbamate

시약·촉매·용매 1

HCID 284Formic Acid용매

실험 절차

182 g (0.7S7 mol) of ethyl N-allyl-N-(1,1-dimethoxyprop -2-yl)-carbamate in 1.5 1 of water are heated under reflux for three hours with 80 ml of formic acid. The mixture is saturated with sodium chloride, the organic phase is separated off and the aqueous phase is extracted twice with 500 ml of methylene chloride each time. The organic solutions are washed with saturated sodium hydrogen carbonate solution until neutral, dried over magnesium sulphate and concentrated, and the residue is distilled.

후처리

  1. customthe organic phase is separated off
  2. extractionthe aqueous phase is extracted twice with 500 ml of methylene chloride each time
  3. washThe organic solutions are washed with saturated sodium hydrogen carbonate solution until neutral,
  4. dry with materialdried over magnesium sulphate
  5. concentrationconcentrated
  6. distillationthe residue is distilled

출처 및 근거

ORD 기록
ord-4a56c24f8bbe4384bb23cced35cc2c6b
출처 데이터셋
uspto-grants-1991_12
특허 번호
US05071999

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