Methylamine → 5-chloro-N-{2-[4-(2-ethoxyethyl)-2-methylphenoxy]ethyl}-6-methyl-N-(N'-methylcarbamoyl)-4-pyrimidine amine
반응식
[Cl:1][C:2]1[C:3]([N:9]([C:25](Cl)=[O:26])[CH2:10][CH2:11][O:12][C:13]2[CH:18]=[CH:17][C:16]([CH2:19][CH2:20][O:21][CH2:22][CH3:23])=[CH:15][C:14]=2[CH3:24])=[N:4][CH:5]=[N:6][C:7]=1[CH3:8].[CH3:28][NH2:29]>C1(C)C=CC=CC=1>[Cl:1][C:2]1[C:3]([N:9]([CH2:10][CH2:11][O:12][C:13]2[CH:18]=[CH:17][C:16]([CH2:19][CH2:20][O:21][CH2:22][CH3:23])=[CH:15][C:14]=2[CH3:24])[C:25](=[O:26])[NH:29][CH3:28])=[N:4][CH:5]=[N:6][C:7]=1[CH3:8]참가 물질
4
실험 절차
Into a solution of 1.0 g of 5-chloro-N-chlorocarbonyl-N-{2-[4-(2-ethoxyethyl)-2-methylphenoxy]ethyl}-6-methyl-4-pyrimidine amine dissolved in 20 ml of toluene was added under stirring 1 ml of an aqueous 40% monomethylamine solution, and the mixture was stirred at room temperature for one hour.