Thionyl Chloride → Acetyl chloride, (benzoyloxy)-

HRID 1461116노트

반응식

[C:1]([O:9][CH2:10][C:11]([OH:13])=O)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.S(Cl)([Cl:16])=O>>[C:1]([O:9][CH2:10][C:11]([Cl:16])=[O:13])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

반응물 2

HCID 24386Thionyl Chloride

HCID 12647149HCID 12647149, 화합물

생성물 1

HCID 10888895Acetyl chloride, (benzoyloxy)-수율 88%

실험 절차

A mixture of 2-(benzoyloxy)acetic acid (12.6 g) and thionyl chloride (15 ml) was refluxed for 3 h. Excess of thionyl chloride was removed in vacuo and the crude (benzoyloxy)acetyl chloride obtained was purified by distillation in vacuo. The yield was 88%. Mp 25°-26° C.

후처리

temperaturewas refluxed for 3 h
customExcess of thionyl chloride was removed in vacuo

출처 및 근거

ORD 기록: ord-894768fca82143b29a962f66aa2071e8
출처 데이터셋: uspto-grants-1991_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05073641

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