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Sodium Bicarbonate → HCID 19979812, 화합물

HRID 1461183
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HRID 1461183 반응식
C(=O)(O)[O-].[Na+].[C:6]1(O)[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9](O)=[N:8][N:7]=1.[CH2:18]([S:26][S:27]C(=N)N)[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25]>O.CO>[CH2:18]([S:26][S:27][C:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]([S:27][S:26][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])=[N:8][N:7]=1)[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25]
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

6

반응물 3

HCID 516892Sodium BicarbonateHCID 19979809HCID 19979809, 화합물HCID 178518942HCID 178518942, 화합물

생성물 1

HCID 19979812HCID 19979812, 화합물수율 91%

시약·촉매·용매 2

HCID 887Methanol용매HCID 962Water용매

실험 절차

A solution of sodium bicarbonate (4.30 g, 0.05 mole) in water (60 ml) was added dropwise to a stirred suspension of the phthalazine-1,4-diol prepared as above (2.91 g, 0.015 mole) and S-n-octylthioisothiourea obtained in step (A) (7.695 g, 0.03 mole) in methanol (70 ml) at 60°-65° C. over 30 minutes. The mixture was stirred at room temperature for a further hour, then filtered giving a yellow solid, which was washed with water and dried giving the product as yellow crystals (6.56 g, 91%).

후처리

  1. filtrationfiltered
  2. customgiving a yellow solid, which
  3. washwas washed with water
  4. customdried

출처 및 근거

ORD 기록
ord-cbf05a0367fa486f8f50545ec1e3cfa0
출처 데이터셋
uspto-grants-1991_12
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US05075020

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