3,4-Dichlorophenol → Rac-4-[2-(3,4-dichloro-phenoxy)-propionylamino]-thiophene-3-carboxylic acid

HRID 14612

반응식

HRID 14612 반응식
C[O:2][C:3]([C:5]1[C:9]([NH:10][C:11](=[O:15])[CH:12](Cl)[CH3:13])=[CH:8][S:7][CH:6]=1)=[O:4].[Cl:16][C:17]1[CH:18]=[C:19]([OH:24])[CH:20]=[CH:21][C:22]=1[Cl:23]>>[Cl:16][C:17]1[CH:18]=[C:19]([CH:20]=[CH:21][C:22]=1[Cl:23])[O:24][CH:12]([CH3:13])[C:11]([NH:10][C:9]1[C:5]([C:3]([OH:2])=[O:4])=[CH:6][S:7][CH:8]=1)=[O:15]

참가 물질

3

반응물 2

HCID 72583,4-DichlorophenolHCID 68688356Rac-4-(2-chloro-propionylamino)-thiophene-3-carboxylic acid methyl ester

생성물 1

HCID 16068683Rac-4-[2-(3,4-dichloro-phenoxy)-propionylamino]-thiophene-3-carboxylic acid

실험 절차

In analogy to Example 2, the title compound was prepared using rac-4-(2-chloro-propionylamino)-thiophene-3-carboxylic acid methyl ester and 3,4-dichlorophenol. MS (m/e): 360.0 (M−H).

출처 및 근거

ORD 기록
ord-dfa3c45841c044c79e13a902739fee12
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07732452B2

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