Methanone, [1-(2-chloroethyl)-4-piperidinyl](4-fluorophenyl)- → 1-{2-[4-(4-Fluorobenzoyl)piperidino]ethyl}-4-(2-fluorobenzyl) piperazine 2,6-dione hydrochloride

HRID 1461743

반응식

HRID 1461743 반응식
[Cl:1][CH2:2][CH2:3][N:4]1[CH2:9][CH2:8][CH:7]([C:10](=[O:18])[C:11]2[CH:16]=[CH:15][C:14]([F:17])=[CH:13][CH:12]=2)[CH2:6][CH2:5]1.[F:19][C:20]1[CH:34]=[CH:33][CH:32]=[CH:31][C:21]=1[CH2:22][N:23]1[CH2:28][C:27](=[O:29])[NH:26][C:25](=[O:30])[CH2:24]1>>[ClH:1].[F:17][C:14]1[CH:15]=[CH:16][C:11]([C:10]([CH:7]2[CH2:8][CH2:9][N:4]([CH2:3][CH2:2][N:26]3[C:25](=[O:30])[CH2:24][N:23]([CH2:22][C:21]4[CH:31]=[CH:32][CH:33]=[CH:34][C:20]=4[F:19])[CH2:28][C:27]3=[O:29])[CH2:5][CH2:6]2)=[O:18])=[CH:12][CH:13]=1

참가 물질

3

반응물 2

HCID 10516150Methanone, [1-(2-chloroethyl)-4-piperidinyl](4-fluorophenyl)-HCID 140987404-[(2-Fluorophenyl)methyl]piperazine-2,6-dione

생성물 1

HCID 148827311-{2-[4-(4-Fluorobenzoyl)piperidino]ethyl}-4-(2-fluorobenzyl) piperazine 2,6-dione hydrochloride

실험 절차

This compound was prepared from 1-(2-chloroethyl)-4-(4-fluorobenzoyl)piperidine and 4-(2-fluorobenzyl) piperazine 2,6-dione according to the process described in Example 3, Stage B.

출처 및 근거

ORD 기록
ord-1aadfbee857c4609ad39722f6b1ca8b4
출처 데이터셋
uspto-grants-1991_12
특허 번호
US05077288

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