Imidazole → HCID 20454106, 화합물

HRID 1462200노트

반응식

HRID 1462200 반응식
[O:1]1[CH2:6][C:5](=S)[NH:4][C:3](=[O:8])[NH:2]1.[NH:9]1[CH:13]=[CH:12][N:11]=[CH:10]1>O1CCOCC1>[N:9]1([C:5]2[CH2:6][O:1][NH:2][C:3](=[O:8])[N:4]=2)[CH:13]=[CH:12][N:11]=[CH:10]1

참가 물질

4

반응물 2

HCID 795ImidazoleHCID 30069082H-1,2,4-Oxadiazin-3(4H)-one, dihydro-5-thioxo-

생성물 1

HCID 20454106HCID 20454106, 화합물수율 56.2%

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

To a solution of 1.0 g (0.0075 mole) of 6H-1,2,4-oxadiazin-3(2H)-one-5(4H)-thione in 50 ml of freshly distilled dry dioxane is added 0.52 g (0.0077 mole) of imidazole. After stirring at room temperature for 17 hours, the solution is filtered, washed with chloroform and dried to give a yield of 0.7 g (56 percent) of 5-(1H-imidazol-1-yl)-6H-1,2,4-oxadiazin-3(2H)-one.

후처리

  1. filtrationthe solution is filtered
  2. washwashed with chloroform
  3. customdried

출처 및 근거

ORD 기록
ord-9118464c35924632a636580a25c244cc
출처 데이터셋
uspto-grants-1984_07
특허 번호
US04459403

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