Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 3-amino-5-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 반응물 | 2-((Methoxy)(4-phenoxyphenyl)methylene)malononitrile | HCID 22347227 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 3-amino-5-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile | HCID 22346784 | — |
반응 단계
1,1-Dicyano-2-methoxy-2-(4-phenoxyphenyl)ethene (22.5 g) and 1,1-dicyano-2-methoxy-2-(4-phenoxyphenyl)ethene oil (15 g) are treated with a solution of hydrazine hydrate (18 mL) in ethanol (25 mL) and heated on the steambath for 1 hour. Ethanol (15 mL) is added followed by water (10 mL). The precipitated solid is collected and washed with ethanol:water (4:1) and then dried in air to give 3-amino-4-cyano-5-(4-phenoxyphenyl)pyrazole as a pale orange solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07732454B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-6c1b8747619e463ca1875ae0e21688f5 |
| 출처 메모 | uspto-grants-2010_06 |