Methanol → 2-[2-(4-Chlorophenyl)-5-(3-thienyl)-4-oxazolyl]acetic acid
반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]([C:19]3[CH:23]=[CH:22][S:21][CH:20]=3)=[C:11]([CH2:13][C:14]([O:16]CC)=[O:15])[N:12]=2)=[CH:4][CH:3]=1.CO.[OH-].[K+]>O>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]([C:19]3[CH:23]=[CH:22][S:21][CH:20]=3)=[C:11]([CH2:13][C:14]([OH:16])=[O:15])[N:12]=2)=[CH:4][CH:3]=1참가 물질
5
실험 절차
6 g of ethyl 2-[2-(4-chlorophenyl)-5-(3-thienyl)-4-oxazolyl]acetate, 150 ml of methanol, 30 ml of water and 2.2 g of potassium hydroxide are treated in the same manner as described in Example 8. 4.9 g of 2-[2-(4-chlorophenyl)-5-(3-thienyl)-4-oxazolyl]acetic acid are thereby obtained.
출처 및 근거
- ORD 기록
- ord-ddfcad6f82624db9bd42f25ab156cdaa
- 출처 데이터셋
- uspto-grants-1984_07
- 특허 번호
- US04460596
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