1,3-Butadiene → 3-Methyl-12-phenyl-1-aza-1,5,9-cyclododecatriene

반응식

[CH:1](=[N:8][CH:9]=[CH:10][CH3:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:12]=[CH:13][CH:14]=[CH2:15]>>[CH3:11][CH:10]1[CH2:4][CH:3]=[CH:2][CH2:1][CH2:15][CH:14]=[CH:13][CH2:12][CH:1]([C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)[N:8]=[CH:9]1

참가 물질

반응물 2

HCID 78451,3-Butadiene

HCID 143013N-benzylidene-propenylamine

생성물 1

HCID 537330893-Methyl-12-phenyl-1-aza-1,5,9-cyclododecatriene

실험 절차

In a manner analogous to that described in Example 1(a) 495 g (3.41 mols) of N-benzylidene-propenylamine is reacted with 1,3-butadiene. The reaction mixture is distilled to yield 750 g (2.97 mols) of 3-methyl-12-phenyl-1-aza-1,5,9-cyclododecatriene as a cis-trans isomeric mixture (cis:trans=65:35); b.p. 112°-113° C./1 Pa; nD20 =1.5505; m.p. (cis isomer)=57°-58° C.

후처리

distillationThe reaction mixture is distilled

출처 및 근거

ORD 기록: ord-a2698f1a764548ca8002dcaa2a65f20b
출처 데이터셋: uspto-grants-1984_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04460790

반응 노트

불러오는 중…