HCID 11805918, 화합물 → Flavan
반응식
[O:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]1[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>C(O)(=O)C.[C].[Pd]>[O:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH:2]1[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1참가 물질
4
실험 절차
The flav-3-ene was catalytically hydrogenated in acetic acid (60 ml) using 10% palladium carbon catalyst (150 mg) at room temperature and a atmospheric pressure. 750 ml hydrogen was absorbed over 3 hr. The reaction mixture was filtered, diluted with water, extracted with toluene, and the evaporated extract chromatographed on neutral alumina, eluting with toluene. The product was recrystallised from ethanol yielding flavan (2.75 g) m.pt. 43°-44° C.
후처리
- customat room temperature
- custom750 ml hydrogen was absorbed over 3 hr
- filtrationThe reaction mixture was filtered
- additiondiluted with water
- extractionextracted with toluene
- extractionthe evaporated extract
- customchromatographed on neutral alumina
- washeluting with toluene
- customThe product was recrystallised from ethanol
출처 및 근거
- ORD 기록
- ord-e163519bfdc04366996388da1b5f07d7
- 출처 데이터셋
- uspto-grants-1984_07
- 특허 번호
- US04461907
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