Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzenesulfinic acid → 2-(Benzenesulfonyl)-5-methoxyoxolane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzenesulfinic acid | HCID 12057 | — |
| 반응물 | 2,5-Dimethoxytetrahydrofuran | HCID 79098 | — |
| 반응물 | Calcium Chloride | HCID 5284359 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2-(Benzenesulfonyl)-5-methoxyoxolane | HCID 19930462 | 55% |
반응 단계
2,5-Dimethoxytetrahydrofuran (17.1 ml, 0.13 M) was added dropwise to a stirred solution of benzenesulphinic acid (17.0 g, 0.12 M) in dry DCM (100ml) containing a suspension of powdered CaCl2 (1.0 g) at room temperature under argon. After 4 h, the solution was washed with water (2×50 ml), dried (Na2SO4) and evaporated. The product was crystallised (diethyl ether/hexane) to give 2-benzenesulphonyl-5-methoxytetrahydrofuran (15 9 g, 55%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05300524 |
| 출처 데이터셋 | uspto-grants-1994_04 |
| ORD ID | ord-6b5822870bbc4b8290e6f4a0e5d4a634 |
| 출처 메모 | uspto-grants-1994_04 |