Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → N-(1-deoxyfructopyranos-1-yl)-D-isoleucine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | D-Isoleucine | HCID 76551 | — |
| 반응물 | (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal | HCID 107526 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | N-(1-deoxyfructopyranos-1-yl)-D-isoleucine | HCID 86747745 | 49.2% |
반응 단계
A dry mixture of 40 ml of methanol and 10 ml of pyridine was added to 100 mg of dry D-isoleucine together with 300 mg of anhydrous glucose, and reaction and purification were carried out as described in Example 9, but making use of smaller-volume chromatography columns. Crystallization of the final product yielded 110 mg of N-(1-deoxyfructopyranos-1-yl)-D-isoleucine. Melting point 142°-144° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05302582 |
| 출처 데이터셋 | uspto-grants-1994_04 |
| ORD ID | ord-811538b30e2940988f965e6fd7175727 |
| 출처 메모 | uspto-grants-1994_04 |