Cumylamine → N-(1-Methyl-1-phenylethyl)-3-oxo-4-azaandrost-5-ene-17beta-carboxamide

HRID 1463946

반응식

[O:1]=[C:2]1[CH2:19][CH2:18][C@@:17]2([CH3:20])[C:4](=[CH:5][CH2:6][C@@H:7]3[C@@H:16]2[CH2:15][CH2:14][C@@:12]2([CH3:13])[C@H:8]3[CH2:9][CH2:10][C@@H:11]2[C:21](O)=[O:22])[NH:3]1.[CH3:24][C:25]([NH2:33])([C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1)[CH3:26]>>[CH3:24][C:25]([NH:33][C:21]([C@H:11]1[CH2:10][CH2:9][C@H:8]2[C@H:7]3[C@H:16]([CH2:15][CH2:14][C@:12]12[CH3:13])[C@:17]1([CH3:20])[C:4]([NH:3][C:2](=[O:1])[CH2:19][CH2:18]1)=[CH:5][CH2:6]3)=[O:22])([C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1)[CH3:26]

참가 물질

반응물 2

HCID 68509Cumylamine

HCID 4754473-Oxo-4-aza-5-androstene-17beta-carboxylic acid

생성물 1

HCID 67750713N-(1-Methyl-1-phenylethyl)-3-oxo-4-azaandrost-5-ene-17beta-carboxamide수율 68%

실험 절차

The title compound was prepared in a yield of 68% in a similar manner to that described in Example 37 by reacting 3-oxo-4-azaandrost-5-ene-17β-carboxylic acid and 1-methyl-1-phenylethylamine.

출처 및 근거

ORD 기록: ord-ad06c0bc5a51468984bae94b12f37946
출처 데이터셋: uspto-grants-1994_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05302621

연결된 노트

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