Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,4-Difluoroaniline → 2,4-Difluorophenyl-3-methylurea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,4-Difluoroaniline | HCID 9709 | — |
| 반응물 | Methyl Isocyanate | HCID 12228 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 2,4-Difluorophenyl-3-methylurea | HCID 21161590 | — |
반응 단계
Methyl isocyanate (9.6 g, 10 mL, 0.174 mol) is added to a solution of 2,4-difluoroaniline (15 g, 0.116 mol) in toluene. The reaction mixture is stirred for 1 hour and filtered to obtain a solid. The solid is washed with hexanes and air-dried to give the title product as an off-white solid, mp 182°-183° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05726126 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-2711ddf9e8434df4b8105ee87a87cff2 |
| 출처 메모 | uspto-grants-1998_03 |