Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Oxobutyronitrile → 2-(2-Chloro-5-pyridylmethylamino)-1-cyano-1-propene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Oxobutyronitrile | HCID 75579 | — |
| 반응물 | 5-(Aminomethyl)-2-chloropyridine | HCID 7020927 | — |
| 생성물 | 2-(2-Chloro-5-pyridylmethylamino)-1-cyano-1-propene | HCID 86747770 | 85% |
반응 단계
1.4 g of 2-chloro-5-pyridylmethylamine and 0.8 g of 1-cyano-2-propanone were mixed and the mixture was stirred at room temperature over night. The solvent was then distilled off and the residue was purified by column chromatography on silica gel to afford 1.7 g of compound No. 528. m.p. 95°-98° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05304566 |
| 출처 데이터셋 | uspto-grants-1994_04 |
| ORD ID | ord-0787945b338f4211b0c021907cfd5215 |
| 출처 메모 | uspto-grants-1994_04 |